Endpoint

How it is used

Trials have a primary endpoint, chosen in advance, and secondary endpoints. A surrogate endpoint is a measurement, such as cholesterol or blood pressure, used instead of a clinical outcome like heart attacks, which takes longer to appear. A trial 'meets' or 'misses' its primary endpoint.

Example sentences

1. The trial met its primary endpoint, a reduction in hospital admissions for heart failure.

2. Blood pressure is only a surrogate endpoint; what really matters is fewer strokes.

Common collocations

• primary endpoint
• secondary endpoint
• surrogate endpoint
• meet the primary endpoint

Related terms

• clinical trialA research study in people that tests whether a new medicine or treatment is safe and works, usually by comparing it with a placebo or an existing treatment.
• randomized controlled trialA study in which participants are put into groups by chance, one receiving the treatment being tested and another a placebo or standard treatment, so results can be fairly compared.
• efficacyThe ability of a drug to produce the wanted effect; in pharmacology, the maximum effect a drug can produce, however high the dose.
• placeboA dummy treatment that looks like the real medicine but contains no active ingredient, used in clinical trials for comparison with the drug being tested.

This word in other fields

The same English word can have a different meaning in another field:

• endpoint · Software Engineering
• endpoint · Web Development
• endpoint · Artificial Intelligence & Machine Learning
• endpoint · Cybersecurity
• endpoint · Chemistry

More terms: Clinical Trials and Drug Development

• double-blind
• informed consent
• preclinical